TCR V Alpha24-J Alpha18 antibody (PE)

Catalog No. ABIN7670257

The Mouse Monoclonal anti- antibody has been validated for FACS. It is suitable to detect in samples from Human.

Quick Overview for TCR V Alpha24-J Alpha18 antibody (PE) (ABIN7670257)

Target: TCR V Alpha24-J Alpha18

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: PE

Application: Flow Cytometry (FACS)

Clone: 6B11

Product Details

Purpose: PE Anti-Human TCR Vα24-Jα18 Antibody[6B11]

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 5 μL/tests

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant

Handling Advice: Please protected from prolonged exposure to light and do not freeze.

Storage: 4 °C

Storage Comment: This product can be stored at 2-8°C for 12 months.

Expiry Date: 12 months

Target Details

Target: TCR V Alpha24-J Alpha18

Alternative Name: TCR Valpha24-Jalpha18

Background: TCR Vα24-Jα18,TCR Vα24-JαQ,invariant NKT cell,iNKT,Encoded by the TCR Vα24-Jα18 germline configuration, Vα24-JαQ is expressed on a subset of NKT cells, namely invariant NKT (iNKT). Vα24-JαQ TCR interacts with the glycolipid loaded MHC class 1b molecule CD1d, inducing activation and subsequent cytokine production. iNKT cells have been implicated in immune regulation, tumor surveillance, and host response to pathogens. While iNKT cells occur at low frequency in the blood, assorted chemokines contribute to their tissue homing potential.